First Bank, Florence Branch Basic Info Reviews Routing Numbers Map & Direction Name: First Bank, Florence Branch Main Office: No Service: Full Service Brick and Mortar Office Location: 452 Second Loop Rd Florence, South Carolina 29505 Florence County View other branches Phone: 843-665-2265 Please enable JavaScript to view the comments powered by Disqus. Routing NumberProcess ACH TransferProcess Wire Transfer053100724YN053104568YY053111700YN053112178YN053202240YN053207397YN253171427YN253171540YN253171728YN253271987YN From: To: